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Mouse Monoclonal Antibody to FOXD3
Item#:
sAP-0493
Size Price Quantity
50.0 ug $320.00
Catalog Number sAP-0493
Product Name Mouse Monoclonal Antibody to FOXD3
Target Molecle FOXD3
Aliases AIS1; HFH2; Genesis; FOXD3
Species Human; Mouse; Monkey
MW 50kDa
Enterez GeneID 27022
General Information FoxD3 is a member of the Forkhead Box family and is characterized by a winged-helix DNA-binding structure and the important role it plays in embryonic development . This transcriptional regulator is required for the maintenance of pluripotency in the pre-implantation and peri-implantation stages of mouse embryonic development and is also required for trophoblast formation. FoxD3 is required for the maintenance of the mammalian neural crest; FoxD3(-/-) mouse embryos fail around the time of implantation with loss of neural crest-derived structures. FoxD3 also forms a regulatory network with Oct-4 and NANOG to maintain the pluripotency of ES cells. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis. Tissue specificity
Immunogen Purified recombinant fragment of human FOXD3 expressed in E. Coli.
Clone MM5G9;
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1. Leuk Lymphoma. 2008 Nov;49(11)
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