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Mouse Monoclonal Antibody to STK11


Item#:
sAP-0491
Size Price Quantity
50.0 ug $320.00
Catalog Number sAP-0491
Product Name Mouse Monoclonal Antibody to STK11
Target Molecle STK11
Aliases PJS; LKB1; STK11
Species Human; Mouse; Monkey
MW 54kDa
Enterez GeneID 6794
General Information Essential role in G1 cell cycle arrest. Phosphorylates and activates members of the AMPK-related subfamily of protein kinases. Tumor suppressor.serine/threonine kinase 11,with two alternatively spliced isoforms,expressed in all tissues,strongly homolog of Xenopus early embryonic kinase 1 (XEEK1),tumor suppressor gene in hamartomas syndrome and in left sided colon carcinogenesis,mutated in sporadic testicular cancer,malignant melanomas and laryngeal tumors,playing a minor role in the development of ovarian carcinoma.LKB1 is a potential target for atherosclerosis and cancer and is shown to be mutated in patients with Peutz-Jeghers cancer syndrome. Tissue specificity
Immunogen Purified recombinant fragment of human STK11 expressed in E. Coli. ; ;
Clone MM4H12;
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide. ; ;
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1. J Cutan Pathol. 2009 Feb;36(2)
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