Mouse Monoclonal Antibody to CSK

Item#:

sAP-0469

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0469
Product Name	Mouse Monoclonal Antibody to CSK
Target Molecle	CSK
Aliases	MGC117393; CSK
Species	Human; Mouse; Monkey; Rat
MW	50kDa
Enterez GeneID	1445
General Information	Carboxy-terminal Src kinase (Csk) is a ubiquitously expressed nonreceptor tyrosine kinase that negatively regulates the Src family kinases (SFK) by phosphorylation of the SFK carboxy-terminal tyrosine. Phosphorylated carboxy-terminal tyrosine binds to the SH2 domain of SFK intramolecularly and leads to folding and inactivation of the SFK . This Csk-catalyzed SFK tyrosine phosphorylation is highly specific and exclusive. The SFK carboxy-terminal tyrosine is the only known physiological substrate of Csk .Tissue specificity
Immunogen	Purified recombinant fragment of human CSK expressed in E. Coli.
Clone	MM5F3;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Oncol Rep. 2009 Oct;22(4)