Mouse Monoclonal Antibody to EIF2AK3

Item#:

sAP-0467

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0467
Product Name	Mouse Monoclonal Antibody to EIF2AK3
Target Molecle	EIF2AK3
Aliases	PEK; WRS; PERK; EIF2AK3
Species	Human
MW	125kDa
Enterez GeneID	9451
General Information	The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.
Immunogen	Purified recombinant fragment of human EIF2AK3 expressed in E. Coli.
Clone	MM5G5;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Biochem J. 1993 Jul 15;293 ( Pt 2)