Mouse Monoclonal Antibody to KLHL22

Item#:

sAP-0461

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0461
Product Name	Mouse Monoclonal Antibody to KLHL22
Target Molecle	KLHL22
Aliases	KELCHL; KLHL22
Species	Human
MW	72kDa
Enterez GeneID	84861
General Information	KLHL22 (kelch-like protein 22) is a 634 amino acid protein that is related to the Drosophilakelch protein, which is required to maintain Actin organization in ovarian ring canals. Mutations affecting Kelch function result in the failure of Kelch to associate with the ring canals and subsequent female sterility. Human KLHL22 protein contains six kelch repeats and one BTB (POZ) domain. The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. There are two isoforms of KLHL22 that are produced as a result of alternative splicing events.
Immunogen	Purified recombinant fragment of human KLHL22 expressed in E. Coli.
Clone	MM7B10;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Acta Neuropathol. 2009 Jun;117(6)