Mouse Monoclonal Antibody to CD86

Item#:

sAP-0459

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0459
Product Name	Mouse Monoclonal Antibody to CD86
Target Molecle	CD86
Aliases	B70; B7-2; LAB72; CD28LG2; MGC34413; CD86
Species	Human
MW	52kDa
Enterez GeneID	942
General Information	This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.Tissue specificity
Immunogen	Purified recombinant fragment of human CD86 expressed in E. Coli.
Clone	MM1B3;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Mol Cancer. 2010 Jan 5;9