Mouse Monoclonal Antibody to GFI1

Item#:

sAP-0450

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0450
Product Name	Mouse Monoclonal Antibody to GFI1
Target Molecle	GFI1
Aliases	SCN2; GFI-1; ZNF163; FLJ94509; GFI1
Species	Human
MW	45kDa
Enterez GeneID	2672
General Information	This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.Expression of GFl1 ranges from the hematopoietic and lymphoid system, to sensory epithelia, lung and parts of the CNS.
Immunogen	Purified recombinant fragment of human GFI1 expressed in E. Coli.
Clone	MM5D7;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. J Biol Chem. 2006 Feb 10;281(6)