Mouse Monoclonal Antibody to SMAD6

Item#:

sAP-0449

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0449
Product Name	Mouse Monoclonal Antibody to SMAD6
Target Molecle	SMAD6
Aliases	MADH6; MADH7; HsT17432; SMAD6
Species	Human
MW	53kDa
Enterez GeneID	4091
General Information	Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD. Binds to regulatory elements in target promoter regions.Tissue specificity
Immunogen	Purified recombinant fragment of human SMAD6 expressed in E. Coli. ; ;
Clone	MM5H3;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Biochim Biophys Acta. 1992 Feb 26;1119(2)