Mouse Monoclonal Antibody to HK1

Item#:

sAP-0437

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0437
Product Name	Mouse Monoclonal Antibody to HK1
Target Molecle	HK1
Aliases	HKI; HXK1; HK1-ta; HK1-tb; HK1-tc; HK1
Species	Human; Rat; Mouse
MW	102kDa
Enterez GeneID	3098
General Information	The hexokinases utilize Mg-ATP as a phosphoryl donor to catalyze the first step of intracellular glucose metabolism, the conversion of glucose to glucose- 6-phosphate. Four hexokinase isoenzymes have been identified, including hexokinase I (HXK I), hexokinase II (HXK II), hexokinase III (HXK III) and hexokinase IV (HXK IV, also designated glucokinase or GCK). Hexokinases I-III each contain an N-terminal cluster of hydrophobic amino acids. Glucokinase lacks the N-terminal hydrophobic cluster. The hydrophobic cluster is thought to be necessary for membrane binding. This is substantiated by the finding that glucokinase has lower affinity for glucose than do the other hexokinases. HK I has been shown to be expressed in brain, kidney and heart tissues as well as in hepatoma cell lines.
Immunogen	Purified recombinant fragment of human HK1 expressed in E. Coli.
Clone	MM7A7;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Genomics. 1993 Jun;16(3)