Mouse Monoclonal Antibody to STAT5B

Item#:

sAP-0427

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0427
Product Name	Mouse Monoclonal Antibody to STAT5B
Target Molecle	STAT5B
Aliases	STAT5; STAT5B
Species	Human
MW	90kDa
Enterez GeneID	6777
General Information	The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.
Immunogen	Purified recombinant fragment of human STAT5B expressed in E. Coli. ;
Clone	MM5B3;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide. ; ;
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Mol Syst Biol. 2007;3