Mouse Monoclonal Antibody to WDR5

Item#:

sAP-0426

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0426
Product Name	Mouse Monoclonal Antibody to WDR5
Target Molecle	WDR5
Aliases	SWD3; BIG-3; WDR5
Species	Human
MW	36.6kDa
Enterez GeneID	11091
General Information	WD-repeat protein 5 (WDR5, also designated BMP-2-induced gene 3 kb or BIG-3) belongs to the family of WD-40 repeat proteins, and is essential for vertebrate development, Hox gene activation and global H3K4 trimethylation. WDR5 is a conserved subunit of Trithorax (TRX) histone methyltransferase complexes that selectively binds to dimethylated Lys4 (K4me2) in Histone H3 to promote K4 trimethylation by TRX. It is expressed in osteoblasts, chondrocytes, osteocytes and marrow stromal cells. The WDR5 protein contains 7 WD-repeats, which may play a role in its function of accelerating osteoblast differentiation.
Immunogen	Purified recombinant fragment of human WDR5 expressed in E. Coli.
Clone	MM7B11;
Isotype	Mouse IgG2b
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide. ;
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. PLoS One. 2009 Sep 21;4(9)