Mouse Monoclonal Antibody to CDC27

Item#:

sAP-0417

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0417
Product Name	Mouse Monoclonal Antibody to CDC27
Target Molecle	CDC27
Aliases	APC3; HNUC; ANAPC3; CDC27Hs; D0S1430E; D17S978E;
Species	Human
MW	91kDa
Enterez GeneID	996
General Information	Cdc27 shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. It is a component of the Anaphase Promoting Complex (APC), which is composed of eight protein subunits and is highly conserved in eucaryotic cells. The APC catalyzes the formation of the cyclin B ubiquitin conjugate that is responsible for the ubiquitin mediated proteolysis of B type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis.
Immunogen	Purified recombinant fragment of human CDC27 expressed in E. Coli. ;
Clone	MM5C12;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide. ;
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. DNA Res. 1997 Oct 31;4(5)