Mouse Monoclonal Antibody to CDKN1B

Item#:

sAP-0397

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0397
Product Name	Mouse Monoclonal Antibody to CDKN1B
Target Molecle	CDKN1B
Aliases	KIP1; MEN4; CDKN4; MEN1B; P27KIP1; CDKN1B
Species	Human
MW	22kDa
Enterez GeneID	1027
General Information	p27 KIP 1 is a cell cycle regulatory mitotic inhibitor of cdk activity. p27 KIP 1 is a candidate tumor suppressor gene, and has been proposed to function as a possible mediator of TGF beta induced G1 arrest. p27 KIP 1 is up regulated in response to antimitogenic stimuli. The increased protein expression of p27 results in cellular arrest by binding to cyclin/Cdk complexes such as cyclin D1/Cdk4. Decreased levels of p27Kip1, mainly due to proteosomal degradation, are found in various epithelial tumors originating from lung, breast, colon, ovary, esophagus, thyroid and prostate.Tissue specificity
Immunogen	Purified recombinant fragment of human CDKN1B expressed in E. Coli.
Clone	MM3D8;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Oncogene. 2004 Mar 11;23(10)