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Mouse Monoclonal Antibody to BMX
Item#:
sAP-0396
Size Price Quantity
50.0 ug $320.00
Catalog Number sAP-0396
Product Name Mouse Monoclonal Antibody to BMX
Target Molecle BMX
Aliases ETK; PSCTK2; PSCTK3; BMX
Species Hunam
MW 78kDa
Enterez GeneID 660
General Information BMX (bone marrow X kinase) is a cytoplasmic tyrosine kinase identified by reverse transcription of mRNA isolated from human bone marrow and mapped to the chromosomal band Xp22.2. The full length protein is 675 amino acids with a tyrosine kinase domain, an amino terminal pleckstrin domain, as well as an SH3 and SH2 domain. Direct comparison of BMX's primary sequence with other kinases showed that this is highly related to the family of BTK/ITK/TEC. BMX kinase is expressed in fetal and adult tissues, with the highest expression in heart, testis, small intestine and colon. It is undetectable in spleen, brain, kidney, and pancreas. Further analysis of mRNA expression showed that BMX is expressed in hematopoietic tissues and neutrophilic granulocytes, and in patients with acute and myeloid leukemia. The levels of BMX mRNA were substantially lower in patients with acute and chronic lymphoid leukemias, thus suggesting that BMX may be important during myelopoiesis.CST
Immunogen Purified recombinant fragment of human BMX expressed in E. Coli. ;
Clone MM1C6;
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1. J Biol Chem. 2007 Mar 16;282(11)
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