Mouse Monoclonal Antibody to SNAI2

Item#:

sAP-0390

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0390
Product Name	Mouse Monoclonal Antibody to SNAI2
Target Molecle	SNAI2
Aliases	SLUG; WS2D; SLUGH1; MGC10182; SNAI2
Species	Human
MW	30kDa
Enterez GeneID	6591
General Information	This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity.The tumor suppressor protein p53 induces Slug expression in ¿-irradiated cells; Slug protects damaged cells from apoptosis by repressing p53-induced transcription of the proapoptotic Bcl-2 family protein Puma. Mutations in this gene may be associated with sporatic cases of neural tube defects.
Immunogen	Purified recombinant fragment of human SNAI2 expressed in E. Coli.
Clone	MM2H5;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide. ;
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Nat Methods. 2005 Aug;2(8)