Mouse Monoclonal Antibody to ICAM1

Item#:

sAP-0383

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0383
Product Name	Mouse Monoclonal Antibody to ICAM1
Target Molecle	ICAM1
Aliases	BB2; CD54; P3.58; ICAM1
Species	Human
MW	57.8kDa
Enterez GeneID	3383
General Information	ICAM1 is a 85-110 kDa single chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. It shares considerable amino acid sequence homology with ICAM3 and with ICAM2. ICAM1 is expressed by activated endothelial cells. It is detected on cells of many other lineages (e.g. epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils), with lower levels that increase in inflammation. ICAM1 is also detected in some carcinoma and melanoma cells. Soluble ICAM1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes. It is the receptor for rhinoviruses and malaria.
Immunogen	Purified recombinant fragment of human ICAM1(28-480aa) expressed in E. Coli. ;
Clone	MM6G12;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide. ;
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. J Mol Biol. 2009 Nov 20;394(1)