Mouse Monoclonal Antibody to ZBTB7B

Item#:

sAP-0364

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0364
Product Name	Mouse Monoclonal Antibody to ZBTB7B
Target Molecle	ZBTB7B
Aliases	THPOK; ZFP67; ZBTB15; c-Krox; hcKrox; ZNF857B; DKFZp686G01254; ZBTB7B
Species	Human
MW	58kDa
Enterez GeneID	51043
General Information	ZBTB7B is a transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. ZBTB7B is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes. It may also function as a repressor of fibronectin and possibly other extracellular matrix genes.
Immunogen	Purified recombinant fragment of human ZBTB7B expressed in E. Coli.
Clone	MM7C12;
Isotype	Mouse lgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Virchows Arch. 2009 Jun;454(6)