Mouse Monoclonal Antibody to AKT2

Item#:

sAP-0355

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0355
Product Name	Mouse Monoclonal Antibody to AKT2
Target Molecle	AKT2
Aliases	PKBB; PRKBB; PKBBETA; RAC-BETA
Species	Human; Rat; Monkey
MW	60kDa
Enterez GeneID	208
General Information	Akt2 (also designated protein kinase B beta or v-akt murine thymoma viral oncogene homolog 2 ), with 481-amino acid protein (about 53kDa), belongs to the AKT serine/threonine protein kinase family, which also includes Akt1 and Akt3. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. Among the members of AKT family, Akt2 is associated with the development of human cancers. Akt2 inhibits cisplatin-induced JNK/p38 and Bax activation through phosphorylation of ASK1 and thus, plays an important role in chemoresistance. Further, Akt2 plays a specific role in muscle differentiation.
Immunogen	Purified recombinant fragment of human AKT2 expressed in E. Coli.
Clone	MM1B6;
Isotype	Mouse IgG2b
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. J Invest Dermatol. 2005 Nov;125(5)