Mouse Monoclonal Antibody to FAK

Item#:

sAP-0351

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0351
Product Name	Mouse Monoclonal Antibody to FAK
Target Molecle	FAK
Aliases	FAK; FADK; FAK1; FRNK; pp125FAK; PTK2
Species	Human; Mouse
MW	119kDa
Enterez GeneID	5747
General Information	This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. At least four transcript variants encoding four different isoforms have been found for this gene, but the full-length natures of only two of them have been determined. Tissue specificity
Immunogen	Purified recombinant fragment of human FAK expressed in E. Coli.
Clone	MM10H7;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. JR Goldenring, KR Shen, HD Vaughan. et al. J. Biol. Chem,1993,268(25)