Mouse Monoclonal Antibody to CHD3

Item#:

sAP-0344

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0344
Product Name	Mouse Monoclonal Antibody to CHD3
Target Molecle	CHD3
Aliases	ZFH; Mi-2a; Mi2-ALPHA; CHD3
Species	Human; Mouse
MW	226kDa
Enterez GeneID	1107
General Information	This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
Immunogen	Purified recombinant fragment of human CHD3 expressed in E. Coli.
Clone	MM2G4;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. J Hepatol. 2009 Apr;50(4)