Mouse Monoclonal Antibody to CD38

Item#:

sAP-0338

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0338
Product Name	Mouse Monoclonal Antibody to CD38
Target Molecle	CD38
Aliases	T10; CD38
Species	Human
MW	34kDa
Enterez GeneID	952
General Information	CD38 is a type II integral membrane glycoprotein which is present on early B and T cell lineages and activated B and T cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B cells, mitogen-activated T cells, monocytes and Ig-secreting plasma cells. CD38 acts as a NAD glycohydrolase in T lym- phocytes. On hematopoietic cells CD38 induces activation, proliferation, and differentiation of mature T and B cells and mediates apoptosis of myeloid and lymphoid progenitor cells. In addition to acting as a signaling receptor, CD38 is also an enzyme capable of producing several calcium-mobilizing metabo- lites, including cyclic adenosine diphosphate ribose (cADPR). CD38 also plays a role in maintaining survival of an invariant NK T (iNKT) cell subset that preferentially contributes to the maintenance of immunological tolerance.
Immunogen	Purified recombinant fragment of human CD38 expressed in E. Coli.
Clone	MM6E12D;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Cancer Gennet Cytogenet. 2008. 187(1)