Mouse Monoclonal Antibody to KDR

Item#:

sAP-0324

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0324
Product Name	Mouse Monoclonal Antibody to KDR
Target Molecle	KDR
Aliases	FLK1; CD309; VEGFR; VEGFR2
Species	Human
MW	152kDa
Enterez GeneID	3791
General Information	KDR has also been designated as VEFR-2 (Vascular endothelial growth factor receptor 2), CD309 (cluster of differentiation 309) and Flk1 (fetal liver kinase 1). Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. KDR is one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.
Immunogen	Purified recombinant extracellular fragment of human KDR (aa20-764) fused with hIgGFc tag expressed in HEK293 cells.
Clone	MM4B4;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Dev Biol. 1998 Feb 15;194(2)