Mouse Monoclonal Antibody to Proteinase 3

Item#:

sAP-0309

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0309
Product Name	Mouse Monoclonal Antibody to Proteinase 3
Target Molecle	Proteinase 3
Aliases	PRTN3; ACPA; CANCA
Species	Human
MW	28kDa
Enterez GeneID	5657
General Information	Proteinase 3, also known as PRTN3. PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. Its exact role in the function of the neutrophil is unknown but in human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis.
Immunogen	Purified recombinant fragment of human Proteinase 3 expressed in E. Coli.
Clone	MM3B4;
Isotype	Mouse IgG2b
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Antibody are purified by protein G affinity chromatography. ; Liquid in PBS containing 50% glycerol and 0.03% sodium azide. ;
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. J Cell Sci. 2005 Jan 15;118(Pt 2)