Mouse Monoclonal Antibody to AGT

Item#:

sAP-0300

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0300
Product Name	Mouse Monoclonal Antibody to AGT
Target Molecle	AGT
Aliases	ANHU
Species	Human
MW	53kDa
Enterez GeneID	183
General Information	AGT, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
Immunogen	Purified recombinant fragment of human AGT expressed in E. Coli.
Clone	MM1B1;
Isotype	Mouse IgG2b
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. J Biol Chem. 2004 Jul 9;279(28)