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Mouse Monoclonal Antibody to PDGFRß
Item#:
sAP-0298
Size Price Quantity
50.0 ug $320.00
Catalog Number sAP-0298
Product Name Mouse Monoclonal Antibody to PDGFRß
Target Molecle PDGFRß
Aliases JTK12; PDGFR; CD140B; PDGFR1; PDGFRB
Species Human, Mouse
MW 190kDa
Enterez GeneID 5159
General Information Platelet-derived growth factor receptor, beta polypeptide, also known as PDGFRB, PDGFRß or CD140B. It is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. This family exist as several disulphide-bonded, dimeric isoforms (PDGF AA, PDGF AB, PDGF BB, PDGF CC and PDGF DD) that bind in a specific pattern to two closely related receptor tyrosine kinases, PDGF receptor a (PDGFRa) and PDGF receptor ß (PDGFRß). These growth factors are mitogens for cells of mesenchymal origin. PDGFRB is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
Immunogen Purified recombinant fragment of human PDGFRß expressed in E. Coli.
Clone MM1A2;
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1. Biochem Biophys Res Commun. 2005 Sep 9;334(4)
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