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Mouse Monoclonal Antibody to MYL3
Item#:
sAP-0283
Size Price Quantity
50.0 ug $320.00
Catalog Number sAP-0283
Product Name Mouse Monoclonal Antibody to MYL3
Target Molecle MYL3
Aliases CMH8; VLC1; MLC1V; MLC1SB
Species Human
MW 22kDa
Enterez GeneID 4634
General Information Myosins are a large superfamily of motor proteins that move along actin filaments, while hydrolyzing ATP. Myosin is the major component of thick muscle filaments, and is a long asymmetric molecule containing a globular head and a long tail. The molecule consists of two heavy chains and four light chains. Activation of smooth and cardiac muscle primarily involves pathways which increase calcium and myosin phosphorylation resulting in contraction. Myosin light chain phosphatase acts to regulate muscle contraction by dephosphorylating activated myosin light chain. MYL3 encodes myosin light chain 3, an alkali light chain also referred to in the literature as both the ventricular isoform and the slow skeletal muscle isoform. Human myosin light chain has clinical application as a cardiac marker. Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy.
Immunogen Purified recombinant fragment of MYL3 expressed in E. Coli.
Clone MM7C1;
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1. Xie B, et al. Biophys Chem. 2003 Oct 1;106(1)
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