Mouse Monoclonal Antibody to PAR4

Item#:

sAP-0177

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0177
Product Name	Mouse Monoclonal Antibody to PAR4
Target Molecle	PAR4
Aliases	PAWR
Species	Human
MW	N/A
Enterez GeneID	5074
General Information	Prostate apoptosis response 4 (Par4) is a 38kD protein originally identified as the product of a gene that is upregulated in prostate tumor cells undergoing apoptosis. It is a leucine zipper and death domain containing protein whose levels increase in neurons undergoing apoptosis as a result of trophic factor withdrawal or exposure to oxidative and metabolic insults. Par4 levels are reported to be increased in their lumbar spinal cord specimens further suggesting a role in neuronal degeneration. The tumor suppressor WT1 represses and activates transcription. The loss and/or imbalance of the dual transcriptional activity of WT1 may contribute to Wilms tumor. Par4 is a WT1 interacting protein that also functions as a transcriptional repressor.
Immunogen	Purified recombinant fragment of PAR4(aa1-330) expressed in E. Coli. ;
Clone	MM3G9H7;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Exp Hematol. 2004 Apr;32(4)