Mouse Monoclonal Antibody to MSH6

Item#:

sAP-0161

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0161
Product Name	Mouse Monoclonal Antibody to MSH6
Target Molecle	MSH6
Aliases	GTBP; HSAP; HNPCC5
Species	Human
MW	N/A
Enterez GeneID	2956
General Information	Defects in MSH6 are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome). HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early onset colorectal carcinoma (crc) and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the western world. MSH6 is central to mismatch DNA repair.
Immunogen	Purified recombinant fragment of MSH6 expressed in E. Coli. ;
Clone	MM3A10H7;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. J Mol Med. 2006,Jul, 84(7)