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Mouse Monoclonal Antibody to IFN-gamma
Item#:
sAP-0133
Size Price Quantity
50.0 ug $320.00
Catalog Number sAP-0133
Product Name Mouse Monoclonal Antibody to IFN-gamma
Target Molecle IFN-gamma
Aliases IFG; IFI; IFNG
Species Human
MW N/A
Enterez GeneID 3458
General Information IFN-gamma (interferon, gamma) is an antiviral and antiparasitic agent produced by CD4+/CD8+ lymphocytes and natural killer cells that undergo activation by antigens, mitogens or alloantigens. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses, including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. The active form of IFN-G is a homodimer with each subunit containing six helices. The dimeric structure of human IFN-G is stabilized by non-covalent interactions through the interface of the helices. IFN-G translated precursor is 166 amino acids, including the 23 amino acid secretory sequence. It is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. Multiple forms exist due to variable glycosylation and under non-denaturing conditions due to dimers and tetramers.
Immunogen Recombinant human IFN-gamma (BioSource company, Cat.No. PHC4033)
Clone MM1B1A4;
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS containing 0.03% sodium azide.
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1. Young HM. Anderson RB. Anderson CR. Auton Neurosci. 2004, May 31,112(1-2)
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