Mouse Monoclonal Antibody to TIP60

Item#:

sAP-0114

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0114
Product Name	Mouse Monoclonal Antibody to TIP60
Target Molecle	TIP60
Aliases	TIP60 (HTATIP)
Species	Human;
MW	60kDa
Enterez GeneID	10524
General Information	HTATIP (HIV-1 Tat interacting protein TIP60, about 60kDa) belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. In addition to the growing number of post-translational histone modifications regulating chromatin structure, cells can also exchange canonical histones with variant histones that can directly or indirectly modulate chromatin structure. There are five major variants of histone H2A
Immunogen	Purified recombinant fragment of human TIP60 expressed in E. Coli.
Clone	MM3F9;
Isotype	Mouse IgG2b
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Sterner, D.E., et al. Microbiol. Mol. Biol 2000 Rev. 64