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Mouse Monoclonal Antibody to MYST1
Item#:
sAP-0113
Size Price Quantity
50.0 ug $320.00
Catalog Number sAP-0113
Product Name Mouse Monoclonal Antibody to MYST1
Target Molecle MYST1
Aliases MOF; KAT8; hMOF
Species Human
MW 53kDa
Enterez GeneID 84148
General Information MYST1 (MYST histone acetyltransferase 1, MOF) belongs to the MYST family of histone acetyltransferases, which are employed in the cell to bring about transcriptional regulation. The MYST family includes MYST1, is named for the founding members MOZ, yeast YBF2 and SAS2, and TIP60. All members of this family contain a MYST region of about 240 amino acids with a canonical acetyl-CoA-binding site and a C2HC-type zinc finger motif. Most MYST proteins also have a chromodomain involved in protein- protein interactions and targeting transcriptional regulators to chromatin. Although MOF is expressed in both males and females, it associates with the X chromosome only in males. MOF contains a zinc-finger domain that is used to contact the globular part of the nucleosome and histone H4. The carboxy terminal domain of human MOF also has histone acetyltransferase activity directed against histones H3 and H2A, a characteristic shared with other MYST family histone
Immunogen Purified recombinant fragment of human MYST1 expressed in E. Coli.
Clone MM8C4C4;
Isotype Mouse IgG2b
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1. ampbell, R.A. et al. 2001, J. Biol. Chem. 276, 9817-9824. ; 2. Chen, D. et al. 2000, Mol. Cell 6, 127-137. ;
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