Mouse Monoclonal Antibody to RSK1

Item#:

sAP-0109

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0109
Product Name	Mouse Monoclonal Antibody to RSK1
Target Molecle	RSK1
Aliases	RSK; HU-1; RSK1; MAPKAPK1A; RPS6KA1
Species	Human;
MW	N/A
Enterez GeneID	6195
General Information	Rsk1 is a member of a family of 90kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine / threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB. RSK proteins possess two separate kinase domains, the C terminal kinase domain and the N terminal kinase domain, separated by a linker region containing a hydrophobic motif. RSK is activated by many stimuli including growth factors, phorbol esters, cAMP, heat shock, and irradiation.
Immunogen	Purified recombinant fragment of human RSK1 expressed in E. Coli.
Clone	MM10B1D7A9;
Isotype	Mouse IgG2b
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Janssen, J.W.G., et al. 1991. Oncogene 6