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Mouse Monoclonal Antibody to CD31


Item#:
sAP-0104
Size Price Quantity
50.0 ug $320.00
Catalog Number sAP-0104
Product Name Mouse Monoclonal Antibody to CD31
Target Molecle CD31
Aliases CD31; PECAM-1; PECAM1
Species Human
MW N/A
Enterez GeneID 5175
General Information CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1), is a type I integral membrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors.It is constitutively expressed on the surface of endothelial cells, and concentrated at the junction between them. The antibody reacts with the murine form of the Platelet-Endothelial Cell Adhesion Molecule. The reactivity of the antibody is restricted to the isoform of the molecule that is selectively expressed by endothelial cells.The antigen is predominantly present at the lateral borders of endothelial cells as described for human PECAM-1.It is also weakly expressed on many peripheral lymphoid cells and platelets.CD31 has been used to measure angiogenesis in association with tumor recurrence. Other studies have also indicated that CD31 and CD34 can be used as markers for myeloid progenitor cells and recognize different subsets of myeloid leukemia infiltrates (granular sarcomas).
Immunogen Purified recombinant fragment of human CD31 expressed in E. Coli.
Clone MM2F7B2;
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1. Hunter, T. 1993. Cell 75
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