Mouse Monoclonal Antibody to PTK6

Item#:

sAP-0096

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0096
Product Name	Mouse Monoclonal Antibody to PTK6
Target Molecle	PTK6
Aliases	BRK; FLJ42088
Species	Human
MW	52kDa
Enterez GeneID	5753
General Information	PTK6 (protein tyrosine kinase 6, BRK or FLJ42088), with 451-amino acid protein (about 52kDa), encods a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Its presence in the nucleus appears to be linked to suppression of tumor progression. The encoded protein has been shown to undergo autophosphory-lation. Very high level in colon and high levels in small intestine and prostate, and low levels in some fetal tissues. And Expressed at low level in some breast tumors, but not in normal breast. Also found in melanocytes, but not expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype.
Immunogen	Purified recombinant fragment of human PTK6 expressed in E. Coli. ; ;
Clone	MM2H12B8;
Isotype	Mouse IgG2b
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Mojica WD et.alHistopathology. 2005 Nov;47(5)