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Mouse Monoclonal Antibody to INHA (Inhibin alpha)


Item#:
sAP-0084
Size Price Quantity
50.0 ug $320.00
Catalog Number sAP-0084
Product Name Mouse Monoclonal Antibody to INHA (Inhibin alpha)
Target Molecle INHA (Inhibin alpha)
Aliases INHA; inhibin, alpha
Species Human;
MW 40kDa
Enterez GeneID 3623
General Information INHA (A-inhibin subunit precursor, inhibin alpha subunit ), also called inhibin (alpha) ,which is located on chromosome 2q33-q36. Inhibin is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises of two subunits,Inhibin A and B. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa cell tumors and can therefore be used as a marker for primary as well as recurrent disease. In addition to their role in endocrine feedback in the reproductive sytem, inhibins subserve local regulatory roles in numerous extragonadal tissues, including brain, adrenal,bone marrow, placenta, and most notably anterior pituitary. Inhibin alpha subunit gene expression is down regulated in human prostate cancer, suggesting a tumor suppressive role.
Immunogen Purified recombinant fragment of human INHA expressed in E. Coli.
Clone MM4A2;
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1. Pause, A. et al. 1994.Nature. 371
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