Mouse Monoclonal Antibody to GSTP1

Item#:

sAP-0078

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0078
Product Name	Mouse Monoclonal Antibody to GSTP1
Target Molecle	GSTP1
Aliases	PI; DFN7; GST3; FAEES3
Species	Human;
MW	23kDa
Enterez GeneID	2950
General Information	GSTP1 (glutathione-S-transferase, pi 1), also called GST3/DFN7, is a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. GSTP1 act like a tumor suppressor gene, which when inactivated leads to tumor growth, and the -class glutathione S-transferase is commonly inactivated by somatic CpGisland hypermethylation in cancers of the prostate, liver, and breast. Methylation of regulatory sequences at the GSTP1 gene locus is found in the vast majority (>90%) of prostate carcinomas and is associated with transcriptional down-regulation.
Immunogen	Purified recombinant fragment of human GSTP1 expressed in E. Coli.
Clone	MM3F2C2;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Crews, C.M, et al. 1992. Science. 258