Mouse Monoclonal Antibody to MAP2K4

Item#:

sAP-0077

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0077
Product Name	Mouse Monoclonal Antibody to MAP2K4
Target Molecle	MAP2K4
Aliases	MAP2K4
Species	Human
MW	N/A
Enterez GeneID	6416
General Information	MAP2K4(mitogen-activated protein kinase kinase 4), which is located on chromosome 17p11.2, with 399-amino acid protein (about 45 kDa), belongs to the family of protein kinases located upstream of the MAP kinases and responsible for their activation has been identified. MEK-4 (also called MEK4/MKK4) activates both p38 and JNK MAP kinases. MKK4 is a central mediator in the stress activated protein kinase signaling pathway that responds to a number of cellular and environmental stressors. By phosphorylating MAP kinases such as JNK,MKK4 can ultimately transmit stress signals to nuclear transcription factors that mediate various processes including proliferation, apoptosis, and differentiation. Its distinct biological functions have been identified for MKK4 including a role in development, hepatogenesis, and metastasis suppression.
Immunogen	Purified recombinant fragment of MAP2K4 expressed in E. Coli.
Clone	MM2D10D8;
Isotype	Mouse Ig M
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Chial B, Persoone G. Environ Toxicol. 2003 Oct;18(5)