Mouse Monoclonal Antibody to ERK2

Item#:

sAP-0073

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0073
Product Name	Mouse Monoclonal Antibody to ERK2
Target Molecle	ERK2
Aliases	ERK; p38; p40; p41; ERT1; MAPK2; PRKM1; P42MAPK; p41mapk; MAPK1
Species	Human; Mouse; Monkey
MW	41kDa
Enterez GeneID	5594
General Information	ERK2 (also designated extracellular-signal-related kinase 2 or mitogen-activated protein kinase 1), with 360-amino acid protein (about 40kDa), belongs to the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of ERK2 requires its phosphorylation by upstream kinases. ERK2 is located in the cytoplasm of resting cells and translocates into the nucleus upon extracellular stimuli by active transport of a dimer. ERK2 is essential for placental development and ERK2 in the trophoblast compartment may be indispensable for the vascularization of the labyrinth.
Immunogen	Purified recombinant fragment of human ERK2 expressed in E. Coli.
Clone	MM4C11;
Isotype	Mouse IgG2a
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Michael H. Shaw, Gordon J. Freeman, Mark F. Scott. J. Immunol., Jun 2006; 176