Mouse Monoclonal Antibody to CIB1

Item#:

sAP-0068

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0068
Product Name	Mouse Monoclonal Antibody to CIB1
Target Molecle	CIB1
Aliases	CIB; KIP; KIP1; SIP2-28
Species	Human
MW	N/A
Enterez GeneID	10519
General Information	CIB1(also designated calcium and integrin binding 1 or calmyrin),with 191-amino acid protein(about 21kDa), belongs to the calcium-binding protein family.CIB1 is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining.CIB1 is an EF-hand-containing protein that binds multiple effector proteins, including the platelet alpha(IIb)beta(3) integrin and several serine/threonine kinases and potentially modulates their function.CIB1 regulates platelet aggregation in hemostasis through a specific interaction with the alpha(IIb) cytoplasmic domain of platelet integrin alpha(IIb)beta(3). CIB1 is also ubiquitously expressed activating and inhibiting protein ligand of the InsP3R.
Immunogen	Purified recombinant fragment of CIB1 expressed in E. Coli.
Clone	MM5A1F5E12;
Isotype	N/A
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Theresa Tretter, Ashley E. Ross, Dominic I. Dordai. J. Exp. Med., Dec 2003; 198