Mouse Monoclonal Antibody to Lck

Item#:

sAP-0064

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0064
Product Name	Mouse Monoclonal Antibody to Lck
Target Molecle	Lck
Aliases	YT16; p56lck; pp58lck
Species	Human
MW	56kDa
Enterez GeneID	3932
General Information	Lck (lymphocyte-specific protein tyrosine kinase), with 509-amino acid protein (about 56kDa), belongs to the Src non-receptor tyrosine kinases family. By virtue of common structural motifs, the Src family is composed of nine members in vertebrates, including Src, Yes, Fgr, Frk, Fyn, Lyn, Hck, Lck and Blk. Lck is expressed predominantly in T cells and is localized to the inner surface of the plasma membrane. Lck is activated after T cell stimulation and is required for T-cell proliferation and IL-2 production. Aberrant expression or activation of Lck kinase has been reported in both lymphoid and nonlymphoid malignancies. In addition, inhibition of Lck has been a target to prevent lymphocyte activation and acute rejection.
Immunogen	Purified recombinant fragment of human Lck expressed in E. Coli.
Clone	MM8E5F9;
Isotype	Mouse IgG2a
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Wen Wang , Scott A. LeMaire, Li Chen. Surgery. 2005 Aug;138(2)