Mouse Monoclonal Antibody to Fibulin 5

Item#:

sAP-0062

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0062
Product Name	Mouse Monoclonal Antibody to Fibulin 5
Target Molecle	Fibulin 5
Aliases	EVEC; UP50; ARMD3; DANCE
Species	Human
MW	N/A
Enterez GeneID	10516
General Information	Fibulin 5(FBLN5), with 448-amino acid protein (about 50kDa), is a recently discovered multifunctional extracellular matrix protein that mediates endothelial cell adhesion through integrin ligation, regulates cell growth and motility in a context-specific manner, and prevents elastinopathy in vivo. Fibulin-5 is abundantly expressed in great vessels and cardiac valves during embryogenesis, and in many adult tissues including the aorta, lung, uterus and skin, all of which contain abundant elastic fibres. Decreased fibulin-5 may contribute to the pathogenesis of aortic dissection by impairing elastic fiber assembly. Fibulin-5 is also a good marker of skin ageing and that the earlier loss of fibulin-5 may involve age-dependent changes in other elastic fibre components.
Immunogen	Purified recombinant fragment of Fibulin 5 expressed in E. Coli.
Clone	MM3F10A5;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Rachael M. Easton, Han Cho, Kristin Roovers. Mol. Cell. Biol., Mar 2005; 25