Mouse Monoclonal Antibody to Akt3

Item#:

sAP-0061

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0061
Product Name	Mouse Monoclonal Antibody to Akt3
Target Molecle	Akt3
Aliases	Akt3
Species	Human
MW	N/A
Enterez GeneID	10000
General Information	Akt3 (also designated protein kinase B gamma or v-akt murine thymoma viral oncogene homolog 3),with 479-amino acid protein (about 53kDa), belongs to the AKT serine/threonine protein kinase family, which also includes Akt1 and Akt2. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake.Akt3 is not required for the maintenance of normal carbohydrate metabolism but is essential for the attainment of normal organ size. Identifying Akt3 as a selective target in melanoma cells also provides new therapeutic opportunities for patients in the advanced stages of this disease.
Immunogen	Purified recombinant fragment of Akt3 expressed in E. Coli.
Clone	MM3B12F3F10;
Isotype	N/A
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. J. Johnson, S. M. Hague, M. Hanson. Neurology, Aug 2004; 63