Mouse Monoclonal Antibody to SNCA

Item#:

sAP-0060

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0060
Product Name	Mouse Monoclonal Antibody to SNCA
Target Molecle	SNCA
Aliases	PD1; NACP; PARK1; PARK4; MGC110988
Species	Human
MW	N/A
Enterez GeneID	6622
General Information	Alpha-synuclein (SNCA), with 140-amino acid protein (about 15kDa), belongs to the synuclein family, which also includes beta- and gamma-synuclein. SNCA is a soluble protein, expressed principally in the brain but also expressed in low concentrations in all tissues examined (except liver). SNCA is implicated in the regulation of dopamine release and transport. The triplication of the SNCA can cause Parkinson disease (PD) and diffuse Lewy body disease within the same kindred. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Immunohistochemistry for SNCA has become the histological technique of choice for the diagnosis for Parkinson's disease, Dementia with Lewy bodies and Multiple System Atrophy.
Immunogen	Purified recombinant fragment of SNCA expressed in E. Coli. ; ;
Clone	MM2B2D1;
Isotype	N/A
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Delphine Boche, Colm Cunningham, Fabian Docagne. Neurobiol Dis. 2006 Feb 27 ; 2. Shizuya Saika. Lab Invest. 2006 Feb;86(2)