Mouse Monoclonal Antibody to EphB4

Item#:

sAP-0056

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0056
Product Name	Mouse Monoclonal Antibody to EphB4
Target Molecle	EphB4
Aliases	HTK; MYK1; TYRO11
Species	Human
MW	N/A
Enterez GeneID	2050
General Information	EPH receptor B4 (EphB4), with 987-amino acid protein (about 108kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. The Eph receptor tyrosine kinases and their ligands, the ephrins, regulate numerous biological processes in developing and adult tissues and have been implicated in cancer progression and in pathological forms of angiogenesis. EphB4 acts as a negative regulator of blood vessel branching and vascular network formation, switching the vascularization program from sprouting angiogenesis to circumferential vessel growth. EphB4 and its ligand ephrinB2 express in several kinds of tumor cells and correlate with tumorigenesis. EphB4 is thus a potential candidate as a predictor of disease outcome in several kinds of tumor and as target for novel therapy.
Immunogen	Purified recombinant fragment of EphB4 expressed in E. Coli.
Clone	MM5B8F7;
Isotype	Mouse IgG2a
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Annie Quan and Phillip J. Robinson. Methods Enzymol. 2005; 404