Mouse Monoclonal Antibody to Dynamin-1

Item#:

sAP-0055

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0055
Product Name	Mouse Monoclonal Antibody to Dynamin-1
Target Molecle	Dynamin-1
Aliases	DNM; DNM1
Species	Human
MW	97kDa
Enterez GeneID	1759
General Information	Dynamin-1 (Dyn1), with 864-amino acid protein (about 95kDa), belongs to the dynamin family. Dynamin-1 (neuron-specific), dynamin-2 (ubiquitously expressed), and dynamin-3 (expressed only in the testis, brain, and lung), constitute the dynamin family. Members of the dynamin family are GPTase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin-1 is phosphorylated in nerve terminals exclusively in the cytosolic compartment and in vitro by protein kinase C. Dynamin-1 is a large GTPase enzyme required in membrane constriction and fission during multiple forms of endocytosis. Dynamin-1 is also a key molecule required for the recycling of synaptic vesicles in neurons, and it has been known that dynamin-1 gene expression is induced during neuronal differentiation.
Immunogen	Purified recombinant fragment of human Dynamin-1 expressed in E. Coli.
Clone	MM3G4B6;
Isotype	Mouse IgG2a
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Shaji Abraham, Deborah W. Knapp, Liang Cheng. Clin Cancer Res. 2006 Jan 15;12(2)