Mouse Monoclonal Antibody to EphA2

Item#:

sAP-0054

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0054
Product Name	Mouse Monoclonal Antibody to EphA2
Target Molecle	EphA2
Aliases	ECK; EPHA2
Species	Human
MW	N/A
Enterez GeneID	1969
General Information	EPH receptor A2 (EphA2), with 976-amino acid protein (about 107 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EphA1, EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, EphA8, EphA10, EphB1, EphB2, EphB3, EphB4 and EphB6 are Eph family receptors for Ephrin family ligands. In normal cells, EphA2 negatively regulates cell growth and invasiveness. EphA2 is overexpressed by many human cancers, and is often associated with poor prognostic features. The clinical significance of the expression of EphA2 was observed in breast, prostate, colon, skin, cervical, ovarian, and lung cancers.EphA2 may serve as a novel target for bladder cancer, colonic adenocarcinoma and ovarian cancer therapy.
Immunogen	Purified recombinant fragment of EphA2 expressed in E. Coli.
Clone	MM1B3C7;
Isotype	Mouse IgM
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Madeleine Toutant, Jeanne-Marie Studler, et al.Mol. Cell. Biol., Nov 2002; 22