Mouse Monoclonal Antibody to FAK

Item#:

sAP-0053

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0053
Product Name	Mouse Monoclonal Antibody to FAK
Target Molecle	FAK
Aliases	FAK; FADK; FAK1; pp125FAK; PTK2
Species	Human
MW	N/A
Enterez GeneID	5747
General Information	Focal adhesion kinase(FAK), with 1074 -amino acid protein(about 118 kDa), is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. FAK is concentrated at the basal edge of only basal keratinocytes that are actively migrating and rapidly proliferating in repairing burn wounds, and is activated and localized to the focal adhesions of spreading keratinocytes in culture. Thus, it has been postulated that FAK may have an important in vivo role in the re-epithelialization of human wounds. FAK protein tyrosine kinase activity has also been shown to increase in cells stimulated to grow by use of mitogenic neuropeptides or neurotransmitters acting through G protein-coupled receptors.
Immunogen	Purified recombinant fragment of FAK expressed in E. Coli.
Clone	MM4A9D6;
Isotype	N/A
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Sigal Gelkop , Gerrald D. Gish, Yael Babichev J Immunol. 2005 Dec 15;175(12)