Mouse Monoclonal Antibody to ZAP70

Item#:

sAP-0052

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0052
Product Name	Mouse Monoclonal Antibody to ZAP70
Target Molecle	ZAP70
Aliases	SRK; STD; TZK
Species	Human
MW	70kDa
Enterez GeneID	7535
General Information	ZAP70 (zeta-chain associated protein kinase), a 70 kDa member of the SYK tyrosine kinase family, plays a central role in lymphocyte activation and development, and is implicated in several immune disorders. ZAP70Controls TCR(T-cell antigen receptor)-linked signal transduction pathways. Its key role in thymocytes development and mature T lymphocytes activation has been illustrated by the characterization of several human immunodeficiencies presenting with mutations in the ZAP70 gene. ZAP70 is also expressed in several types of B-cell neoplasm and is easily detected by immunohistochemistry, providing a useful prognostic marker in patients with chronic lymphocytic leukaemia.
Immunogen	Purified recombinant fragment of human ZAP70 expressed in E. Coli.
Clone	MM3D2A4;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Kazushige Ogawa, Hiroki Wada, Noriyoshi Okada J Cell Sci. 2006 Feb 1;119(Pt 3)