Mouse Monoclonal Antibody to GLP

Item#:

sAP-0049

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0049
Product Name	Mouse Monoclonal Antibody to GLP
Target Molecle	GLP
Aliases	GLP
Species	Human
MW	N/A
Enterez GeneID	79813
General Information	Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted from enteroendocrine L cells in response to ingested nutrients. The closely related peptides glucagon-like peptide (GLP-1) and glucagon have opposing effects on blood glucose. GLP-1 induces glucose-dependent insulin secretion in the pancreas, while glucagon stimulates gluconeogenesis and glycogenolysis in the liver. Glucagon is processed from a large precursor, proglucagon, in a tissue-specific manner in pancreatic alpha-cells. The identification of a hybrid peptide acting as both a GLP-1 agonist and a glucagon antagonist would provide a novel approach for the treatment of type 2 diabetes.
Immunogen	Purified recombinant fragment of GLP expressed in E. Coli.
Clone	MM1B7B4;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Romanov VV et.al Oncogene. 2005,Oct 13; 24(45)