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Mouse Monoclonal Antibody to GAPDH
Item#:
sAP-0033
Size Price Quantity
50.0 ug $320.00
Catalog Number sAP-0033
Product Name Mouse Monoclonal Antibody to GAPDH
Target Molecle GAPDH
Aliases G3PD; GAPD; MGC88685
Species Human
MW 37kDa
Enterez GeneID 2597
General Information Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. It catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The enzyme exists as a tetramer of identical chains. Besides its functioning as a glycolytic enzyme in cytoplasm, recent evidence suggest that mammalian GAPDH is also involved in a great number of intracellular proceses such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. During the last decade a lot of findings appeared concerning the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death, age- related neuronal diseases, such as Alzheimer¿s and Huntington¿s disease.
Immunogen Purified recombinant fragment of human GAPDH expressed in E. Coli. ;
Clone MM1A10;
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1. 1993. Biotechnology (N Y) 11

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